Season 21
104 episodes · Sep 19, 2022
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S21E1Johnny Knoxville; Olivia Cooke; BLACKPINK
Sep 19, 202241mJimmy welcomes guests Johnny Knoxville and Olivia Cooke. Musical performance by BLACKPINK.
S21E2Kathy Griffin; Chad Kroeger and JT Parr; Madison Cunningham
Sep 20, 202241mJimmy welcomes guests Kathy Griffin, and Chad Kroeger and JT Parr. Musical performance by Madison Cunningham.
S21E3John Boyega; Tyler James Williams; Weezer
Sep 21, 202242mJimmy welcomes guests John Boyega and Tyler James Williams. Musical performance by Weezer
S21E4Allison Janney; Chris Estrada; Frankie Quiñones; Yung Gravy
Sep 22, 202241mJimmy welcomes guests Allison Janney, Chris Estrada, and Frankie Quiñones. Musical performance by Yung Gravy.
S21E5Amy Schumer, Charlamagne Tha God, Run the Jewels
Sep 26, 202241mJimmy welcomes comic Amy Schumer, TV host Charlamagne Tha God, and a musical performance by Run the Jewels.
S21E6David Letterman, Tracy Morgan
Sep 27, 202241mJimmy welcomes TV host David Letterman and actor Tracy Morgan.
S21E7Mila Kunis, Ramy Youssef, Future
Sep 28, 202241mJimmy welcomes actress Mila Kunis, actor Ramy Youssef, and a musical performance by Future.
S21E8Ben Stiller, Desus Nice, Yeah Yeah Yeahs
Sep 29, 202241mJimmy welcomes producer Ben Stiller, TV personality Desus Nice, and a musical performance by Yeah Yeah Yeahs.
S21E9Jason Bateman, Action Bronson
Sep 30, 202241mJimmy welcomes actor Jason Bateman and a musical performance by Action Bronson.
S21E10Charlie Hunnam, Iliza Shlesinger, NAV, Don Toliver
Oct 3, 202241mCharlie Hunnam ("Shantaram"), Iliza Shlesinger ("All Things Aside"), Musical Guests NAV feat. Don Toliver
S21E11Norman Reedus, Danielle Deadwyler, Miranda Lambert
Oct 4, 202241mJimmy welcomes actor Norman Reedus, actress Danielle Deadwyler, and a musical performance by Miranda Lambert.
S21E12Keanu Reeves, Judd Apatow, Phoenix
Oct 5, 202241mKeanu Reeves ("BRZRKR: Vol. 2"), Judd Apatow ("Bros"), Musical Guests Phoenix
S21E13David Spade, FLO, Mookie Betts
Oct 6, 202241mActor David Spade (podcast series, "Fly on the Wall with Dana Carvey and David Spade"); professional baseball player Mookie Betts (documentary "Jackie Robinson: Get to the Bag", Los Angeles Dodgers); Flo performs.
S21E14Magic Johnson, Fortune Feimster, Wet Leg
Oct 10, 202241mFormer professional basketball player Magic Johnson; comic Fortune Feimster; Wet Leg performs.
S21E15Jamie Lee Curtis, Lucas Bravo, Midland, Jon Pardi
Oct 11, 202241mActress Jamie Lee Curtis; actor Lucas Bravo; Midland and Jon Pardi perform.
S21E16Jessica Chastain, Maren Morris
Oct 12, 202241mActress Jessica Chastain; Maren Morris talks and performs.
S21E17George Clooney, Julia Roberts, Omar Apollo
Oct 13, 202241mActors George Clooney and Julia Roberts ("Ticket to Paradise"); Omar Apollo performs.
S21E18Josh Gad, Pamela Adlon, Ariel Elias
Oct 24, 202241mActor Josh Gad; actress Pamela Adlon; comic Ariel Elias.
S21E19Charlize Theron, Lewis Hamilton, Armani White
Oct 25, 202241mActress Charlize Theron; race car driver Lewis Hamilton; Armani White performs.
S21E20Lupita Nyong'o, Danai Gurira, Letitia Wright, Duran Duran
Oct 26, 202241mActresses Lupita Nyong'o, Danai Gurira and Letitia Wright ("Black Panther: Wakanda Forever"); Duran Duran performs.
S21E21Quentin Tarantino, Tenoch Huerta, Edgar Winter
Oct 27, 202241mFilmmaker Quentin Tarantino; actor Tenoch Huerta; Edgar Winter sits in with Cleto and the Cletones.
S21E22Gwyneth Paltrow, Patton Oswalt
Oct 31, 202241mActress Gwyneth Paltrow; comic Patton Oswalt.
S21E23Mindy Kaling, Frank Grillo, Goose
Nov 1, 202241mActress Mindy Kaling; actor Frank Grillo; Goose performs.
S21E24Nick Kroll, Yvonne Strahovski, Viagra Boys
Nov 2, 202241mNick Kroll, Yvonne Strahovski, Viagra Boys
S21E31Amy Adams, Maya Rudolph, Jenna Ortega
Nov 15, 202241mAmy Adams, Maya Rudolph, Jenna Ortega, Bush
S21E33Patrick Dempsey, Nicholas Hoult
Nov 17, 202241mPatrick Dempsey, Nicholas Hoult, the Backseat Lovers, Billy Gibbons
S21E38David Harbour, Lisa Ann Walter
Nov 30, 202241mDavid Harbour, Lisa Ann Walter, Thee Sacred Souls
S21E40George Lopez, Haley Lu Richardson
Dec 5, 202241mGeorge Lopez, Haley Lu Richardson, Madi Diaz
S21E41Janelle Monáe, Sadie Sink, Rita Wilson
Dec 6, 202241mJanelle Monáe, Sadie Sink, Rita Wilson, Smokey Robinson
S21E42Will Ferrell, Colson "Machine Gun Kelly" Baker
Dec 7, 202241mWill Ferrell, Colson "Machine Gun Kelly" Baker, the Linda Lindas
S21E46Margot Robbie, Jeremy Allen White
Dec 14, 202241mMargot Robbie, Jeremy Allen White, the White Buffalo
S21E48Seth Rogen, Diego Calva
Jan 3, 202341mSeth Rogen, Diego Calva, Aoife O'Donovan featuring Allison Russell
S21E49Anna Kendrick, Jermaine Fowler
Jan 4, 202341mAnna Kendrick, Jermaine Fowler, Sabrina Carpenter
S21E50Laura Dern, Jeremy Allen White
Jan 5, 202341mLaura Dern, Jeremy Allen White, Matt Maeson
S21E52Austin Butler, Bella Ramsey, Iggy Pop, Peyton Manning, Eli Manning
Jan 9, 202341mAustin Butler, Bella Ramsey, Iggy Pop, Peyton Manning, Eli Manning
S21E53Octavia Spencer, Ramon Rodríguez, Renee Rapp
Jan 10, 202341mOctavia Spencer, Ramon Rodríguez, Renee Rapp
S21E56Danny DeVito, Lucy DeVito
Jan 16, 202341mDanny DeVito, Lucy DeVito, Travis Bennett, A Boogie wit da Hoodie
S21E58Jennifer Lopez, Chris Perfetti, Fall Out Boy
Jan 18, 202341mJennifer Lopez, Chris Perfetti, Fall Out Boy
S21E59Lily Tomlin, Jane Fonda, Rita Moreno, Sally Field, Jacob Latimore
Jan 19, 202341mLily Tomlin, Jane Fonda, Rita Moreno, Sally Field, Jacob Latimore
S21E60David Duchovny, Zach Shallcross
Jan 23, 202341mDavid Duchovny, Zach Shallcross, Lukas Graham, Mickey Guyton
S21E61Julia Louis-Dreyfus, Rose Byrne, Bobby Cannavale
Jan 24, 202341mJulia Louis-Dreyfus, Rose Byrne, Bobby Cannavale
S21E63George Clooney, Snoop Dogg, Coldplay
Jan 26, 202341mGeorge Clooney, Snoop Dogg, Coldplay
S21E64Salma Hayek Pinault, Billy Crudup, Justine Skye
Jan 30, 202341mSalma Hayek Pinault, Billy Crudup, Justine Skye
S21E65Pamela Anderson, Mike Lindell, Fall Out Boy
Jan 31, 202341mPamela Anderson, Mike Lindell, Fall Out Boy
S21E66Nick Offerman, Kerry Condon, Sofia Carson, Diane Warren
Feb 1, 202341mNick Offerman, Kerry Condon, Sofia Carson, Diane Warren
S21E67Reese Witherspoon, Wesley Kimmel, "Science Bob" Pflugfelder
Feb 2, 202341mReese Witherspoon, Wesley Kimmel, "Science Bob" Pflugfelder
S21E68Cate Blanchett, Patrick Mahomes, Dave Franco
Feb 13, 202341mCate Blanchett, Patrick Mahomes, Dave Franco
S21E69Milo Ventimiglia, Charles Barkley, Paramore
Feb 14, 202341mMilo Ventimiglia, Charles Barkley, Paramore
S21E70Orlando Bloom, Lauren Ash, Jordan Davis
Feb 15, 202341mOrlando Bloom, Lauren Ash, Jordan Davis
S21E71Katy Perry, Lionel Richie, Mike Epps, Beck
Feb 16, 202341mKaty Perry, Lionel Richie, Mike Epps, Beck
S21E74Anthony Mackie, Chris Distefano, Gracie Abrams
Feb 23, 202341mAnthony Mackie, Chris Distefano, Gracie Abrams
S21E84Jennifer Hudson, Donnie Yen, Larkin Poe
Mar 20, 202341mJennifer Hudson, Donnie Yen, Larkin Poe
S21E85Julie Bowen, Jamie Demetriou, Depeche Mode
Mar 21, 202341mJulie Bowen, Jamie Demetriou, Depeche Mode
S21E86Molly Shannon, Giancarlo Esposito, Nickel Creek
Mar 22, 202341mMolly Shannon, Giancarlo Esposito, Nickel Creek
S21E87Jeff Goldblum, Teyana Taylor
Mar 23, 202341mJeff Goldblum, Teyana Taylor, Jeff Goldblum & the Mildred Snitzer Orchestra
S21E88Chris Pine, Dave Burd, The War and Treaty
Mar 27, 202341mChris Pine, Dave Burd, The War and Treaty
S21E91Viola Davis, Julius Tennon, Brett Goldstein, Daniel Caesar
Mar 30, 202341mViola Davis, Julius Tennon, Brett Goldstein, Daniel Caesar
S21E93Carol Burnett, Wendi McLendon-Covey
Apr 11, 202341mCarol Burnett, Wendi McLendon-Covey, Metallica
S21E96Freddie Highmore, Amanda Peet, Dinner Party
Apr 17, 202341mFreddie Highmore, Amanda Peet, Dinner Party
S21E98Patrick Stewart, Bridget Everett, Gorillaz featuring Beck
Apr 19, 202341mPatrick Stewart, Bridget Everett, Gorillaz featuring Beck
S21E99Jake Gyllenhaal, Whitney Cummings, boygenius
Apr 20, 202341mJake Gyllenhaal, Whitney Cummings, boygenius
S21E100James Corden, Richard Madden, They Might Be Giants
Apr 24, 202341mJames Corden, Richard Madden, They Might Be Giants
S21E101John Mulaney, India Amarteifio, Cannons
Apr 25, 202341mJohn Mulaney, India Amarteifio, Cannons
S21E102Pierce Brosnan, Abby Ryder Fortson, New West
Apr 26, 202341mPierce Brosnan, Abby Ryder Fortson, New West
S21E104Charlie Day, Padma Lakshmi, Bebe Rexha
May 1, 202341m1. Charlie Day ("Fool's Paradise") 2. Padma Lakshmi ("Taste the Nation with Padma Lakshmi") 3. Musical Guest Bebe Rexha